VWF (von Willebrand Factor) Is a Critical Mediator of Deep Vein Thrombosis in a Mouse Model of Diet-Induced Obesity.

CONCLUSIONS: This study demonstrates the critical role of VWF in the complex, thrombo-inflammatory state of obesity. It adds to the growing rationale for targeting VWF-specific interactions in thrombotic disease. PMID: 32967458 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32967458?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 23, 2020 Category: Cardiology Authors: Michels A, Dwyer CN, Mewburn J, Nesbitt K, Kawecki C, Lenting P, Swystun LL, Lillicrap D Tags: Arterioscler Thromb Vasc Biol Source Type: research