IJERPH, Vol. 17, Pages 6936: Are Advanced Glycation End Products in Skin Associated with Vascular Dysfunction Markers? A Meta-Analysis

IJERPH, Vol. 17, Pages 6936: Are Advanced Glycation End Products in Skin Associated with Vascular Dysfunction Markers? A Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186936 Authors: Alicia Saz-Lara Celia Álvarez-Bueno Vicente Martínez-Vizcaíno Blanca Notario-Pacheco Irene Sequí-Dominguez Iván Cavero-Redondo Evidence exists regarding the association between advanced glycation end products and different cardiovascular disease subclinical processes, such as arterial stiffness and atherosclerosis. With this systematic review and meta-analysis, we aimed to provide a synthesis of the evidence regarding the association of arterial stiffness measured by pulse wave velocity and atherosclerosis measured by carotid intima media thickness with skin autofluorescence. A systematic search was performed using: MEDLINE (PubMed), SCOPUS, and Web of Science, until 30 March 2020. Cross-sectional studies or baseline data from prospective longitudinal studies were considered. The DerSimonian and Laird method was used to calculate the pooled estimates of correlation coefficients and the corresponding 95% confidence intervals (CI) for the association of pulse wave velocity and carotid intima media thickness with skin autofluorescence. Twenty-five studies were included in the systematic review and meta-analysis, including 6306 subjects. The pooled correlation coefficient was 0.25 (95% CI: 0.18, 0.31) for pulse wave velocit...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research