Increased ABCA1 (ATP-Binding Cassette Transporter A1)-Specific Cholesterol Efflux Capacity in Schizophrenia.

CONCLUSIONS: Patients with schizophrenia have increased concentrations of atherogenic apoB-containing lipoproteins, decreased concentrations of large HDL particles, but enhanced ABCA1-mediated CEC. In this population, preventative strategies should focus on reducing atherogenic lipoproteins rather than increasing CEC.
PMID: 32907370 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 9, 2020 Category: Cardiology Authors: Luquain-Costaz C, Kockx M, Anastasius M, Chow V, Kontush A, Jessup W, Kritharides L Tags: Arterioscler Thromb Vasc Biol Source Type: research