Favorable Outcomes of Liver Transplantation from Controlled Circulatory Death Donors Using Normothermic Regional Perfusion Compared to Brain Death Donors

Background. Liver transplantation (LT) from controlled donation after circulatory death (cDCD) was initiated in France in 2015 under a protocol based on the use of normothermic regional perfusion (NRP) before organ procurement. The aim was to compare outcomes following cDCD LT with NRP and donation after brain death (DBD) LT. Methods. This is a multicenter retrospective study comparing cDCD LT with NRP and DBD LT. A case-matched study (1:2) was performed using the variables such as recipient and donor age, indication of LT. Results. A total of 50 patients from the cDCD group were matched to 100 patients from the DBD group. From postoperative days 1–4, serum transaminase release was significantly lower in the cDCD group compared to the DBD group (P
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—Liver Source Type: research