Gastric goblet cell carcinoma concurrent with a neuroendocrine tumor.

Gastric goblet cell carcinoma concurrent with a neuroendocrine tumor. Pathol Res Pract. 2020 Sep;216(9):153092 Authors: Imam R, Imam A, Atlan K, Mintz Y, Khoury T, Grozinsky-Galsberg S, Oleinikov K, Pikarsky AJ, Khalaileh A Abstract Goblet cell carcinoma, a tumor that is assumed to originate from crypt base stem cells, is a distinct type of tumor, that occurs typically in the appendix, however, extra-appendiceal locations were also described in few cases. We herein present a unique case of a 48-year-old male with a diagnosis of primary gastric Goblet cell carcinoma that was initially discovered at the time of an endoscopy performed to evaluate an unremitting abdominal pain that was accompanied by remarkable weight loss; four polypoid fragments of the gastric mucosa were sent for histopathologic examination which showed a moderately differentiated goblet cell carcinoma in addition to classical neuroendocrine tumor. Later, laparoscopic D2 total gastrectomy with appendectomy were performed and confirmed the previously mentioned findings along with a normal histopathology of the appendix. PMID: 32825959 [PubMed - as supplied by publisher]
Source: Pathology, Research and Practice - Category: Pathology Authors: Tags: Pathol Res Pract Source Type: research