Impact of HIV on the survival of hepatocellular carcinoma in hepatitis C virus-infected patients

Background: Previous studies have suggested that hepatocellular carcinoma (HCC) has an aggressive presentation and a shorter survival in people with HIV (PWH). This could be due to later diagnosis or lower rates of HCC treatment, and not to HIV infection itself. Aim: : To assess the impact of HIV on HCC survival in hepatitis C virus (HCV)-infected patients. Methods: Multicenter cohort study (1999–2018) of 342 and 135 HCC cases diagnosed in HIV/HCV-infected and HCV-monoinfected patients. Survival after HCC diagnosis and its predictors were assessed. Results: HCC was at Barcelona-Clinic Liver-Cancer (BCLC) stage 0/A in 114 (33%) HIV/HCV-coinfected and in 76 (56%) HCV-monoinfected individuals (P 
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research