Opioid Overdose Deaths with Buprenorphine Detected in Postmortem Toxicology: a Retrospective Analysis.

CONCLUSION: Decedents with buprenorphine detected on toxicology testing commonly had documented polysubstance use. Although data are limited, buprenorphine may provide some risk mitigation against full agonist opioid overdose including fentanyl. Further work should explore the use of postmortem concentrations of buprenorphine, norbuprenorphine, and other opioid metabolites to determine the role of buprenorphine in fatal overdose pharmacology. PMID: 32648229 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32648229?dopt=Abstract

Source: Journal of Medical Toxicology - July 8, 2020 Category: Toxicology Authors: Wightman RS, Perrone J, Scagos R, Krieger M, Nelson LS, Marshall BDL Tags: J Med Toxicol Source Type: research