PACAP neuropeptide promotes Hepatocellular Protection via CREB-KLF4 dependent autophagy in mouse liver Ischemia Reperfusion Injury

Conclusion: Current study documents the essential neural regulation of PACAP-promoted autophagy in hepatocellular homeostasis in OLT, which provides the emerging therapeutic principle to combat hepatic IRI in OLT.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Zhengze Xue, Yu Zhang, Yuanxing Liu, Cheng Zhang, Xiu-da Shen, Feng Gao, Ronald W. Busuttil, Shusen Zheng, Jerzy W. Kupiec-Weglinski, Haofeng Ji Tags: Research Paper Source Type: research