Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting

Conclusion: These combined data unearthed a remarkably enhanced tumor-killing efficacy of our CuET nanomedicines through nuclear targeting. This work may open a new research area of repurposing DSF as innovative therapeutic agents to treat breast cancer and its metastases.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Liting Ren, Wenya Feng, Jie Shao, Juan Ma, Ming Xu, Ben-Zhan Zhu, Nanfeng Zheng, Sijin Liu Tags: Research Paper Source Type: research