Long non-coding RNA TCL6 enhances preferential toxicity of paclitaxel to renal cell carcinoma cells

Conclusions: TCL6 effectively sensitizes RCC to PTX mainly through downregulation of miR-221. Our results suggest that PTX combined with TCL6 might be a potentially more effective chemotherapeutic approach for renal cancer.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Zhizhao Chen, Quan Zhuang, Ke Cheng, Yingzi Ming, Yujun Zhao, Qifa Ye, Sheng Zhang Tags: Research Paper Source Type: research