From Rare Copy Number Variants to Biological Processes in ADHD.

CONCLUSIONS: Integration of a stringent filtering procedure in CNV studies with suitable bioinformatics approaches can identify ADHD candidate genes at increased levels of credibility. The authors' analytic pipeline provides additional insight into the molecular mechanisms underlying ADHD and allows prioritization of genes for functional validation in validated model organisms.
PMID: 32600152 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - June 29, 2020 Category: Psychiatry Authors: Harich B, van der Voet M, Klein M, Čížek P, Fenckova M, Schenck A, Franke B Tags: Am J Psychiatry Source Type: research