Contributions to the lymphatic filariasis elimination programme and post-elimination surveillance in China by NIPD-CTDR.
Contributions to the lymphatic filariasis elimination programme and post-elimination surveillance in China by NIPD-CTDR.
Adv Parasitol. 2020;110:145-183
Authors: Sun DJ, Fang Y, Huang Y, Zhang Y
Abstract
China was once one of the most heavily endemic for lymphatic filariasis (LF), with a heavy disease burden. Due to decades of sustained efforts, LF was eliminated from China in 2007. The historical tales in the control and elimination of LF in China and current post-elimination surveillance are reviewed and concluded. In the course of LF control and elimination, National Technical Steering Group for Filariasis Control and Research, and Collaborating Research Group on the Transmission Threshold of Filariasis, led by the National Institute of Parasitic Diseases, carried out researches, developed control measures, and applied in practical control and surveillance. The main of the results include: in theoretical study, (1) formulating the microfilaria rate below 1% as the transmission threshold of filariasis, (2) developing anti-filarial drugs and establishing animal model for drug screening, (3) studying the vectorial capacity of mosquitoes transmitted filariasis; in clinical diagnostic and therapy, (1) developing antigens for serological diagnostics, (2) studying different administration regimes for alleviating the side-response of diethylcarbamazine (DEC), (3) studying on the recurrence of acute adenolymphangitis and lymphadenitis of m...
Source: Advances in Parasitology - Category: Parasitology Authors: Sun DJ, Fang Y, Huang Y, Zhang Y Tags: Adv Parasitol Source Type: research
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