Impact of PSMA PET/CT in prostate cancer patient ’s clinical management: a pictorial essay of interesting cases with histologic confirmation

DiscussionIn this pictorial essay and review, the meaning of high PSMA expression in neovasculature and uncommon PCa metastatic spread were addressed. Furthermore, recent information about the possible explanation of (1) PCa metastases without PSMA expression due to dedifferentiation and specific PCa subtypes, and (2) some discordant findings on PSMA expression evaluated by PET/CT and immunohistochemistry related to the anti-PSMA antibody used in each technique is presented.
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research