The status of FOXP3 gene methylation in pediatric systemic lupus erythematosus.

CONCLUSIONS: The FOXP3 gene methylation in children with SLE was significantly higher than healthy subjects, which could possibly affect the level of gene expression. Therefore, one of the causes of increased immune response in SLE can be the lower expression of FOXP3 by hypermethylation of this gene. PMID: 32475613 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32475613?dopt=Abstract

Source: Allergologia et Immunopathologia - May 28, 2020 Category: Allergy & Immunology Authors: Hanaei S, Sanati G, Zoghi S, Gharibzadeh S, Ziaee V, Rezaei N Tags: Allergol Immunopathol (Madr) Source Type: research