Impact of gender and race on expectations and outcomes in total knee arthroplasty.

Impact of gender and race on expectations and outcomes in total knee arthroplasty. World J Orthop. 2020 May 18;11(5):265-277 Authors: Perez BA, Slover J, Edusei E, Horan A, Anoushiravani A, Kamath AF, Nelson CL Abstract BACKGROUND: Total joint arthroplasty is one of the most common surgeries performed in the United States with total knee arthroplasty (TKA) being one of the most successful surgeries for restoring function and diminishing pain. Even with the demonstrated success of TKA and a higher prevalence of arthritis and arthritis related disability among minorities, racial and gender disparity remains a constant issue in providing care for the adult reconstruction patient. AIM: To assess the role of demographics and expectations on differences in perioperative patient reported outcomes (PRO) following TKA. METHODS: One hundred and thirty-three patients scheduled for primary unilateral TKA secondary to moderate to severe osteoarthritis were enrolled in this two-institution prospective study. Validated PRO questionnaires were collected at four time points. Statistical analysis was conducted to determine the impact of gender, ethnic background and expectation surveys responses to assess PRO at these time points. RESULTS: Females were associated with worse preoperative Knee Injury and Osteoarthritis Outcome Scores (KOOS) for symptoms, pain, and activities of daily living. African Americans were associated with worse KOOS for pain, activities o...
Source: World Journal of Orthopaedics - Category: Orthopaedics Tags: World J Orthop Source Type: research

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Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
In this study, the “tailored” group underwent seven days of monitoring using an accelerometer, the results were downloaded, analysed and an individualised pacing plan developed by the therapists. The plan was intended to highlight times when the person had high or low levels of activity (as compared with their own average, and averages drawn from previous studies of people with the same diagnosis), and to point out associations between these activity levels and self reported symptoms. Participants were then provided with ideas for changing their activity levels to optimise their ability to sustain activity and ...
Source: HealthSkills Weblog - Category: Anesthesiology Authors: Tags: 'Pacing' or Quota Chronic pain Clinical reasoning Coping Skills Coping strategies Occupational therapy Pain conditions Research function Motivation pain management self management Therapeutic approaches values Source Type: blogs
Arthritis Research UK, the UK’s leading arthritis charity, is today launching a major nationwide campaign to reveal the true impact of arthritis across society. The campaign will highlight that, either directly or indirectly, arthritis impacts everyone in the UK. The campaign will also highlight that there are over 10 million people living with arthritis and the condition can cause high levels of daily pain and fatigue.As part of the launch, Arthritis Research UK is releasing The Nation’s Joint Problem report which reveals the current and future impact of two major forms of the condition, osteoarthritis (O...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
In conclusion, documentation is important, a critical part of advocacy and the development process at the larger scale. It isn't just words, but rather a vital structural flow of information from one part of the larger community to another, necessary to sustain progress in any complex field. We would all do well to remember this - and to see that building this documentation is an activity in which we can all pitch in to help. Evidence Suggests that, at Least in Earlier Stages, Alzheimer's Disease Blocks Rather than Destroys Memories https://www.fightaging.org/archives/2017/07/evidence-suggests-that-at-least-in-ea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This report sets out why musculoskeletal conditions must be included in future plans to address multimorbidity and makes seven clear recommendations for change.Musculoskeletal conditions affect around 10 million people across the UK, and are often found in people with other long-term conditions. The report reveals that among people over 45 years with a major long-term condition, more than 30% also have arthritis. By age 65, almost half of people with a heart, lung or mental health problem also have arthritis. Conversely, 80% of people with osteoarthritis have at least one other long-term condition such as hypertension...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
In this study we demonstrate the use of clustered regularly interspaced short palindromic repeats (CRISPR)-based epigenome editing to alter cell response to inflammatory environments by repressing inflammatory cytokine cell receptors, specifically TNFR1 and IL1R1. This has applications for many inflammatory-driven diseases. It could be applied for arthritis or to therapeutic cells that are being delivered to inflammatory environments that need to be protected from inflammation." In chronic back pain, for example, slipped or herniated discs are a result of damaged tissue when inflammation causes cells to create ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSIONS: The quality of the evidence examining physical activity and exercise for chronic pain is low. This is largely due to small sample sizes and potentially underpowered studies. A number of studies had adequately long interventions, but planned follow-up was limited to less than one year in all but six reviews.There were some favourable effects in reduction in pain severity and improved physical function, though these were mostly of small-to-moderate effect, and were not consistent across the reviews. There were variable effects for psychological function and quality of life.The available evidence suggests physica...
Source: Cochrane Database of Systematic Reviews - Category: Journals (General) Authors: Tags: Cochrane Database Syst Rev Source Type: research
Results of a new survey released today have revealed that Great Britain is a nation of 'put up and shut up' when it comes to workplace health.Over 2,000 people were questioned about their attitudes and experience regarding health and the workplace. Results showed that:1 in 5 (20%) of people are worried they won't be fit enough to continue working in the next year.39% don't feel confident discussing their workplace health with their employer.A third of people (33%) with a long-term condition felt their colleagues don't understand the impact of their condition.Over 1 in 7 (15%) wouldn't disclose a long-term health ...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
Background: The Mediterranean diet has positively influenced various medical conditions, but only a paucity of studies has considered the relation between the Mediterranean diet and quality of life (QOL) among people living in North America. Objective: We investigated whether a higher adherence to the Mediterranean diet (aMED) was associated with better QOL and decreased pain, stiffness, disability, and depression in a large cohort of North Americans from the Osteoarthritis Initiative. Design: aMED was evaluated through a validated Mediterranean diet score categorized into quintiles. Outcomes of interest were QOL [assessed...
Source: American Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Nutritional Epidemiology Research Articles, Research Need: Role of Nutrition in Health Maintenance, Research Need: Role of Nutrition in Medical Management Nutritional epidemiology and public health Source Type: research
Abstract BACKGROUND: The Mediterranean diet has positively influenced various medical conditions, but only a paucity of studies has considered the relation between the Mediterranean diet and quality of life (QOL) among people living in North America. OBJECTIVE: We investigated whether a higher adherence to the Mediterranean diet (aMED) was associated with better QOL and decreased pain, stiffness, disability, and depression in a large cohort of North Americans from the Osteoarthritis Initiative. DESIGN: aMED was evaluated through a validated Mediterranean diet score categorized into quintiles. Outcomes of...
Source: The American Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Am J Clin Nutr Source Type: research
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