Low Serum Bicarbonate and CKD Progression in Children.

CONCLUSIONS: In children with glomerular disease, low bicarbonate was linked to a higher risk of CKD progression. Resolution of low bicarbonate was associated with a lower risk of CKD progression. Fewer than one half of all children with low bicarbonate reported treatment with alkali therapy. Long-term studies of alkali therapy's effect in patients with pediatric CKD are needed.
PMID: 32467307 [PubMed - as supplied by publisher]

Source: Clinical Journal of the American Society of Nephrology : CJASN - May 27, 2020 Category: Urology & Nephrology Authors: Brown DD, Roem J, Ng DK, Reidy KJ, Kumar J, Abramowitz MK, Mak RH, Furth SL, Schwartz GJ, Warady BA, Kaskel FJ, Melamed ML Tags: Clin J Am Soc Nephrol Source Type: research