Inside San Francisco ’s Ambitious Plan to Bring Universal Coronavirus Testing to An Entire U.S. City

Public health experts can’t say it enough: If the U.S. is going to beat COVID-19, the country needs to ramp up testing. But there’s no single blueprint for cities and states to follow as they respond to that call. Some, like Los Angeles, are going big. In late April, L.A. became the first major city to offer free testing to any resident. Others, like San Francisco, are doing things in a more progressive style, with goals that are just as ambitious. The latter is strategizing from a place of strength. Thanks to some of the nation’s earliest stay-at-home orders, San Francisco has, so far, flattened the curve with relative success. Businesses around the city have been allowed to reopen for curbside pickup. And key to continuing on the path back to normality is continually testing residents, city officials say, with a focus on “vulnerability” above all else. Over the past 11 weeks, since San Francisco began analyzing tests at city labs rather than shipping them off to Atlanta, officials have been gradually widening the circle of who is eligible to get one. The decision not to let just anyone sign up was partly about limited resources. It took time for the city to stabilize its supply chain. But public health officials also wanted to prioritize those who were most at risk. At first, data about risk factors were limited, with officials focused on simple criteria like whether someone had traveled to China. Since then, the calculation has gotten more co...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news

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In addition to comparisons with Spanish Flu in 1918-19, there are other episodes in the 20th century from which lessons have been learned
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
Italy recorded 130 new deaths from the COVID-19 epidemic on Friday against 156 the day before, the Civil Protection Agency said, while the daily tally of new cases rose marginally to 652 from 642 on Thursday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Under-20s appear 56% less likely to contract Covid-19, preliminary evidence suggestsCoronavirus – latest updatesSee all our coronavirus coverageChildren are about half as likely as adults to become infected with coronavirus, according to scientists who reviewed data gathered by contact tracing and population screening studies around the world.The study, which will feed into the debate on when to open schools, found that children and young adults under the age of 20 appear 56% less likely to contract the virus than the over-20s, a finding that supports the idea that children are unlikely to play a major role in spread...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Health Coronavirus outbreak Infectious diseases Microbiology Science Society World news Epidemics Children Source Type: news
Contributors : Zijie Zhang ; Mijia Lu ; Jianrong LiSeries Type : OtherOrganism :N6 –methyladenosine (m6A) is the most abundant internal mRNA modification in eukaryotes, and it plays an important role in RNA metabolism and function. Recent studies have revealed that viral RNA m6A modification can play an anti-viral or pro-viral role depending on the virus. However, whether m6A me thylation can modulate replication of coronaviruses, which cause some severe human and animal diseases such as Coronavirus Disease 2019 (COVID-19), remains unknown. Here, we determined that m6A modifications of porcine epidemic diarrhea coron...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Source Type: research
Authors: Hua L, Zhu H, Liu H Abstract Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by a coronavirus called SARS Coronavirus 2 (SARS-CoV-2). It has been observed that COVID-19 mainly spreads via respiratory tract, contact and digestive tract. Due to the particularity of profession, ophthalmic medical workers need to be in close contact with patients, so they have a higher risk of SARS-CoV-2 infection. In this paper, therefore, the self-protection of medical workers in ophthalmology clinic during COVID-19 epidemic was summarized, so as to improve the occupational protection measures for medical...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Conclusions: To the best of our knowledge, this is the first report focusing on COVID-19 infection in a lymphoma patient undergoing intensive immunochemotherapy. For those patients being treated with immunochemotherapy in epidemic areas, a reduced dose intensity of intensive chemotherapy should be considered, and the effect of immunotherapies such as rituximab on COVID-19 infection should be considered. The impacts of anti-cancer treatment on COVID-19 infection need to be explored further.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
In this study, we found that PEDV infection induced significant IFN-λ expression in type I IFN-defective Vero E6 cells, but virus-induced endogenous IFN-λ did not reduce PEDV titers. Moreover, we demonstrated that PEDV escaped IFN-λ responses by substantially upregulating the suppressor of cytokine signaling protein 1 (SOCS1) expression, which impaired the induction of IFN-stimulated genes (ISGs) and dampened the IFN-λ antiviral response and facilitated PEDV replication in Vero E6 cells. We further showed that PEDV infection increased SOCS1 expression by decreasing host miR-30c-5p expression. Mi...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
To investigate the early epidemic of COVID-19, a total of 176 confirmed COVID-19 cases in Shiyan city, Hubei province, China were surveyed. Our data indicated that the rate of emergence of early confirmed COVID-19 cases in Hubei province outside Wuhan was dependent on migration population, and the second-generation of patients were family clusters originating from Wuhan travelers. Epidemiological investigation indicated that the reproductive number (R0) under containment strategies was 1.81, and asymptomatic SARS-CoV-2 carriers were contagious with a transmission rate of 10.7%. Among the 176 patients, 53 were admitted to t...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Retired doctors in Sheffield say their struggles show challenges government ’s system will faceCoronavirus – latest updatesSee all our coronavirus coverageA group of retired doctors who set up the UK ’s first Covid-19 contact-tracing scheme has warned that the government system faces major challenges after they struggled to persuade health and care workers to self-isolate.Dr Bing Jones, a retired Sheffield GP, helped start the group a month ago out of frustration thatcontact tracing had been abandoned in England. “We sat down and thought: this is a major omission – a schoolboy error. We have g...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Sheffield Medical research Health policy Society UK news Source Type: news
As a hospice chaplain, I know that the path through grief is mourning. Music can meet us on the path and help us keep walking.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Music Coronavirus (2019-nCoV) Funerals and Memorials Hospice Care Chaplains Epidemics Deaths (Fatalities) Source Type: news
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