Molecules, Vol. 25, Pages 2396: Pretreatment of Anthocyanin from the Fruit of Vitis coignetiae Pulliat Acts as a Potent Inhibitor of TNF- α Effect by Inhibiting NF-κB-Regulated Genes in Human Breast Cancer Cells

In conclusion, this study demonstrates that the anthocyanins isolated from the fruits of Vitis coignetiae Pulliat acts as an inhibitor of TNF-α induced NF-κB activation, and subsequent downstream molecules involved in cancer proliferation, invasion, adhesion, angiogenesis, and thus have anti-metastatic activities in MCF-7 breast cancer cells.

Source: Molecules - May 20, 2020 Category: Chemistry Authors: Anjugam Paramanantham Min Jeong Kim Eun Joo Jung Arulkumar Nagappan Jeong Won Yun Hye Jung Kim Sung Chul Shin Gon Sup Kim Won Sup Lee Tags: Article Source Type: research