Green synthesis of silver nanoparticles and their applications as an alternative antibacterial and antioxidant agents.

Green synthesis of silver nanoparticles and their applications as an alternative antibacterial and antioxidant agents. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110901 Authors: Yousaf H, Mehmood A, Ahmad KS, Raffi M Abstract Antimicrobial resistance is a complex global health challenge today. Discovery and development of new natural alternates with novel targets is utmost priority. In this experiment, alternative antibiotic agents in the form of silver nanoparticles (SNPs) and Achillea millefolium L. extracts were evaluated for antibacterial and antioxidant activity. The SNPs were synthesized using aqueous, ethanol and methanol extracts of A. millefolium and were monitored by a color change and UV-vis spectroscopy. The size and shape of the nanoparticles were determined through scanning electron microscopy and phase was assessed through X-ray diffraction. The SNPs were shown to have an average diameter of 20.77, 18.53 and 14.27 nm with spherical, rectangular and cubical shapes, synthesized from aqueous, ethanol and methanol extract respectively. The response of biomolecules present in plant extract during the formation of SNPs was analyzed by Fourier transform infrared spectrometry, showing polyphenols, proteins, carboxylic acid and alcohol are involved in the formation of SNPs. The plant extracts and SNPs were then studied for their antibacterial potential against common human pathogens such as gram-positive bacteria (Staphyloc...
Source: Appl Human Sci - Category: Physiology Authors: Tags: Mater Sci Eng C Mater Biol Appl Source Type: research