Recent Advances in Asialoglycoprotein Receptor and Glycyrrhetinic Acid Receptor-Mediated and/or pH Responsive Hepatocellular Carcinoma-Targeted Drug Delivery.

CONCLUSION: The multifunctional DDS may prolong systemic circulation, continuously release drugs, increase drugs tumor accumulation at targeted site,enhance anticancer effect, and reduce side effects both in vitro or vivo. But it is rarely used to investigate MDR of HCC, it is need to further study before in clinical.
PMID: 32368967 [PubMed - as supplied by publisher]

Source: Current Medicinal Chemistry - May 3, 2020 Category: Chemistry Authors: Li YL, Zhu XM, Liang H, Orvig C, Chen ZF Tags: Curr Med Chem Source Type: research