Conformational analysis by NMR and molecular dynamics of adamantane-doxorubicin prodrugs and their assemblies with β-cyclodextrin: A focus on the design of platforms for controlled drug delivery.

This study proves that Ad-h-Dox prodrug can be an optimum prodrug and act as a building block for a more complex drug transport system.
PMID: 32359883 [PubMed - as supplied by publisher]

Source: Bioorganic and Medicinal Chemistry - April 21, 2020 Category: Chemistry Authors: González-Méndez I, Aguayo-Ortiz R, Sorroza-Martínez K, Solano JD, Porcu P, Rivera E, Dominguez L Tags: Bioorg Med Chem Source Type: research