A comparative evaluation of dexmedetomidine and midazolam in pediatric sedation: A meta-analysis of randomized controlled trials with trial sequential analysis.

CONCLUSIONS: Given that more satisfactory sedation at separation from parents and less incidence of emergence agitation, dexmedetomidine is preferred for pediatric sedation. However, compared with midazolam, the superiority of dexmedetomidine in providing adequate sedation at mask induction and postoperative analgesic effects has not yet been defined. PMID: 32347647 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32347647?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - April 28, 2020 Category: Neuroscience Authors: Lang B, Zhang L, Zhang W, Lin Y, Fu Y, Chen S Tags: CNS Neurosci Ther Source Type: research