SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications
The current COVID-19 pandemic started several months ago and is still exponentially growing in most parts of the world – this is the most recent and alarming update. COVID-19 requires the collaboration of nearly 200 countries to curb the spread of SARS-CoV-2 while gaining time to explore and improve treatment options especially for cardiovascular disease (CVD) and immunocompromised patients, who appear to be at hi gh-risk to die from cardiopulmonary failure. Currently unanswered questions are why elderly people, particularly those with pre-existing comorbidities seem to exhibit higher mortality rates after SARS-CoV-2 infection and whether intensive care becomes indispensable for these patients to prevent mult i-organ failure and sudden death.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Sonja Gro ß, Christopher Jahn, Sarah Cushman, Christian Bär, Thomas Thum Source Type: research
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