Cutaneous Mycobacterium haemophilum infection: A rare cutaneous manifestation in a patient with Crohn's disease

A 66-year-old woman with Crohn's disease received adalimumab therapy for 3 years. She developed some erythematous induration throughout her lower legs (Fig. 1). The nodules became tender and spread to the hands and elbows within 3 months (Fig. 2). Skin biopsy revealed chronic dermatitis with marked necrotizing panniculitis (Fig. 3). Acid-fast staining was positive (Fig. 4). External consultation suggested Mycobacterium haemophilum infection; thus, adalimumab therapy was ceased and combination therapy with clarithromycin, ciprofloxacin, and ethambutol was commenced.

Source: Digestive and Liver Disease - April 23, 2020 Category: Gastroenterology Authors: Chih-Jung Chen, Hsu-Heng Yen Tags: Image of the Month Source Type: research