Clinical pharmacokinetics and pharmacodynamics of ivosidenib in patients with advanced hematologic malignancies with an IDH1 mutation

ConclusionsIvosidenib 500-mg QD has favorable pharmacokinetic and pharmacodynamic profiles in patients with advanced hematologic malignancies with an IDH1 mutation.Clinical trial registrationClinicalTrials.gov NCT02074839.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research