Risk factors and results of hemispherotomy reoperations in children.
CONCLUSIONS: Patients with malformations of cortical development have a higher risk of seizure recurrence, and these malformations comprised the main etiology in the reoperation series. Failure of an initial hemispherotomy usually occurs due to incomplete disconnection and needs to be extensively assessed. Outcomes of reoperation are most often favorable, with acceptable complication rates. PMID: 32234979 [PubMed - in process]
Conclusions: Blood gas changes such as hypoxemia and respiratory acidosis were among the factors statistically associated with the development of symptomatic seizures in patients with respiratory diseases. Additionally, hypoxemia, hypercapnia, and respiratory acidosis were correlated with mortality in patients hospitalized for respiratory system diseases who requested consultations for seizures.RESUMO Objetivo: Convuls ões são uma condição neurológica comumente vivenciada durante o período de acompanhamento após distúrbios sistêmicos ou metabólicos. O obj...
Publication date: Available online 1 June 2020Source: Epilepsy &BehaviorAuthor(s): Diane L. Teagarden, Matthew L. Morton, Nicholas J. Janocko, Olivia Groover, Hannah K. Villarreal, Latasha Evans, Daniel L. Drane, Ioannis Karakis
The new indication is based on the THEMIS trial, which entered patients with CAD and type 2 diabetes without previous MI or stroke and showed clinical benefit, but also bleeding concerns.FDA Approvals
Publication date: Available online 1 June 2020Source: Stem Cell ResearchAuthor(s): Alessia Arbini, James Gilmore, Mary D. King, Kathleen M. Gorman, Janusz Krawczyk, Veronica McInerney, Timothy O'Brien, Sanbing Shen, Nicholas M. Allen
Why is it that all those who have become eminent in philosophy or politics or poetry or the arts are clearly of an [ill-tempered] temperament, and some of them to such an extent as to be affected by diseases caused by black bile, as is said to have happened to [Hercules] among the heroes? For he appears to have been of this nature, and that is why epileptic afflictions were called by the ancients ‘the sacred disease…’—The Complete Works of Aristotle (1984), Edited by Jonathan Barnes
An experimental gene therapy for hemophilia A from BioMarin Pharmaceutical Inc. — promising a one-shot fix for the genetic cause of the bleeding disorder — continues to hold patients' bleeds to less than one a year after four years. The results of the ongoing study are important as San Rafael-based BioMarin's (NASDAQ: BMRN) gene therapy, called Roctavian and known scienti fically as valoctogene roxaparvovec, nears an Aug. 21 decision date from the Food and Drug Administration. If approved, it…
Conclusions Retroperitoneoscopic approach is a good alternative for the treatment of large impacted ureteral stones, large pielic stones and for non-functional kidney removal due to stone disease. In expert hands, it can be safely used with a good SFR. The combination with ICG or other endourological techniques is feasible, allowing higher SFR.
Conditions: Pelvic Ring Fracture; Pelvic Bleeding; Polytrauma Intervention: Sponsor: BG Trauma Center Tuebingen Completed
CONCLUSION: Although TPO-RAs long term efficacy and safety still require further investigations, their use is gradually expanding in clinical practice of children with ITP. PMID: 32473624 [PubMed - as supplied by publisher]
The Food and Drug Administration approved a medication for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women.FDA Approvals