Tacrolimus Levels after Direct Acting Anti-Viral Therapy in Hepatitis C Heart Transplantation

Hepatitis C (HCV) organs have been increasingly utilized in solid organ transplantation since the advent of curative direct acting anti-viral (DAA) therapy. Despite the adoption of this strategy, many unanswered questions remain regarding the management of immunosuppression. In two small case series of liver transplant recipients, tacrolimus concentrations have been shown to decrease with clearance of HCV viremia. We seek to describe our experience and clinical implications in our cardiac transplant population.

Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: K.L. Morris, J.P. Adlam, A. Haleem, A. Patel, R. Garcia-Cortes, S. Chaudhry, J. Proctor, G. Zanotti, M.N. Walsh, C. Salerno, M. Bochan, A. Ravichandran Tags: (397) Source Type: research