Obesity Leads to Increased Mortality in Pediatric Heart Transplant Recipients - A Pediatric Heart Transplant Society Study

This study is the first large scale study to evaluate the prevalence of obesity in pediatric HT recipients and its effects on cardiac allograft vasculopathy (CAV) and graft survival.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (187) Source Type: research

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Authors: Ng CM, Satvinder K, Koo HC, Yap RWK, Mukhtar F Abstract Involving school-age children in the preparation of healthy meals is shown to be associated with positive eating behavior. Yet, it remains unclear whether this can extend to their nutritional status. The present study aimed to determine the association of school-age children's psychosocial factors (knowledge, attitude, practice, self-efficacy) towards healthy meal preparation with their nutritional status (BMI-for-age, waist circumference, body fat percentage). Stratified random sampling was used to select primary schools (n = 8) in Kuala L...
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
Regional efforts to control the spread of COVID-19 have so far proven successful. Image Credit: Pacific CommunityBy William W. EllisTORONTO, May 29 2020 (IPS) By now, the impact of COVID19 on our daily lives has been well documented, especially in advanced economies. Anxiety about the future continues to grow everywhere. Much of the corporate news coverage we consume has focused on the toll this pandemic will take on mainland countries. Often neglected, however, is the unique position Pacific Island States find themselves in. Globally, there are close to 6 million confirmed cases of COVID19. According to the Pacific Commu...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Climate Change Economy & Trade Featured Financial Crisis Global Headlines Health Humanitarian Emergencies Labour Multimedia Podcast TerraViva United Nations Secretariat of the Pacific Community (SPC) Source Type: news
Obesity has dramatically increased over the last 30 years and reaches according to World Health Organization dimensions of a global epidemic. The obesity-associated chronic low-level inflammation contributes to severe comorbidities and directly affects many immune cells leading to immune dysfunction and increased susceptibility to infections. Thus, prophylaxis against vaccine-preventable diseases is crucial, yet the responsiveness to several vaccines is unclear under obesity. In order to assess the responsiveness to tick-borne encephalitis (TBE) vaccine, we revaccinated 37 obese individuals and 36 normal-weight controls wi...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In this study, we investigated the effects of the GATA family of transcription factors on the browning process.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
PMID: 32453345 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Am J Clin Nutr Source Type: research
The United States has seen a significant increase in the number of incarcerated individuals, increasing from 250,000 to 6.6 million prisoners over the last three decades(1). Given the obesity epidemic in the United States, it is not surprising that significant numbers of these prisoners are obese and suffer from obesity related co-morbidities. While the overall prevalence of obesity among prisoners is lower than the general population, inmates frequently gain excessive weight while incarcerated, with rates of obesity as high as 75% upon release from prison(2).
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Controversies in Bariatric Surgery Source Type: research
CONCLUSIONS: The STEP program evaluates the efficacy and safety of semaglutide 2.4 mg subcutaneously once weekly in a broad population. The trials will provide insights on WM in people with obesity with and without type 2 diabetes and on long-term follow-up. PMID: 32441473 [PubMed - in process]
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Obesity (Silver Spring) Source Type: research
Authors: Holly JMP, Biernacka K, Perks CM Abstract Introduction: Preclinical, clinical, and population studies have provided robust evidence for an important role for the insulin-like growth factor (IGF) system in the development of prostate cancer.Areas covered: An overview of the IGF system is provided. The evidence implicating the IGF system in the development of prostate cancer is summarized. The compelling evidence culminated in a number of clinical trials of agents targeting the system; the reasons for the failure of these trials are discussed.Expert opinion: Clinical trials of agents targeting the IGF system...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Abstract The consumption of ultra-processed foods is one of the main drivers of the global obesity and non-communicable disease (NCDs) epidemic1 . It is well known that obesity is associated with a low intensity chronic inflammatory state that creates a suboptimal immune response,2 which negatively affects the prognosis of COVID-193 . The epidemic of obesity and COVID-19 can be viewed as a syndemic as they negatively interact with one another to exacerbate the course of disease, leading to greater complications and severe illness. Together, they create a simultaneous and significant burden on the health system4 . ...
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Obesity (Silver Spring) Source Type: research
Abstract Diabetes mellitus is the most prevalent endocrine disease in the world and is likely to be the major epidemic in human history. In current years, many modern anti-diabetic medicines have been produced and introduced into the markets, however, long-term treatment of diabetes using synthetic drugs is limited. Medicinal plants play a great role in the treatment of diabetes. Many medicinal plants and their related traditional treatments for diabetes are used throughout the world and represent promising alternatives for the management of diabetes treatment. Metabolomics researches on diabetes have contributed ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
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