Metformin protects rotenone-induced dopaminergic neurodegeneration by reducing lipid peroxidation.

CONCLUSIONS: Results showed that metformin treatment attenuated dopaminergic neuron loss in SN induced by rotenone by decreasing lipid peroxidation. PMID: 32207092 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32207092?dopt=Abstract

Source: Pharmacological Reports - March 22, 2020 Category: Drugs & Pharmacology Authors: Ozbey G, Nemutlu-Samur D, Parlak H, Yildirim S, Aslan M, Tanriover G, Agar A Tags: Pharmacol Rep Source Type: research