Outcomes of Locally Advanced Sinonasal Cancer in the Modern Era: Surgery and Adjuvant Therapy remains an Optimal Treatment Strategy

Locally advanced sinonasal cancer (LA-SC) remains a challenge to manage given the lack of prospective studies and the rarity of these lesions. Surgical resection and adjuvant radiation has traditionally been associated with improved outcomes over primary radiation/chemoradiation (RT/CRT). Advances in systemic therapy, radiation, endoscopic surgery and skull base resection as well as increasing use of induction chemotherapy in some centers necessitates re-evaluation of outcomes between surgery and primary RT/CRT approaches.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Non-squamous Cell Malignancies of the Head and Neck: thyroid, sarcomas, skin cancers, salivary gland and sinus cancers Source Type: research