Association between breath methane concentration and visceral fat area: a population-based cross-sectional study
High visceral fat area (VFA) is a stronger predictor of cardiovascular disease and overall
mortality, compared with body mass index (BMI) and waist circumference (WC). Recent reports
demonstrate that obesity is related to breath gas, which is produced by the intestinal microflora.
However, these studies define obesity using BMI, not VFA. In this population-based cross-sectional
study, we investigated the relationship between breath gases (methane and hydrogen) and both VFA and
BMI. A total of 1033 participants (62% women; age [mean ± standard deviation] 54.4 ± 14.9 years) in
the 2015 Iwaki Health Promotion Project in Japan were enrolled in the study. Breath samples were
collected using a breath bag and analyzed by gas chromatography. VFA was measured using a visceral
fat meter. The proportion of methanogenic bacteria to total intestinal microbiota was measured by
polymerase chain reaction and 16S rRNA gene sequencing analysis. Our analysis revealed a significant
association betw...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Naoki Ozato, Shinichiro Saito, Tohru Yamaguchi, Mitsuhiro Katashima, Itoyo Tokuda, Kaori Sawada, Yoshihisa Katsuragi, Masanori Kakuta, Seiya Imoto, Kazushige Ihara and Shigeyuki Nakaji Source Type: research
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