Initial and relapse prodromes in adult patients with episodes of bipolar disorder: A systematic review.

CONCLUSIONS.: For adult patients with BD, initial and relapse prodromes of manic, hypomanic, and depressive episodes were identified. It is proposed that the most frequent prodromes found in this review be incorporated into a smartphone app that monitors the functioning of people at risk of BD and patients who have already been diagnosed. Data from this app would constitute a relevant source of big data. PMID: 32093795 [PubMed - in process]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research

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Sleep disturbance plays several key roles in bipolar disorder (BD). From a diagnostic perspective, insomnia and hypersomnia are criteria for a depressive episode, while decreased need for sleep is a highly specific symptom for a manic episode. Sleep disturbance is the most common prodromal symptom preceding mania, and the duration of sleep observed early in the course of psychiatric hospitalization may predict the speed of recovery from a manic episode. Even during euthymic periods, patients with BD frequently struggle with sleep difficulties, which may affect quality of life and the choice of pharmacotherapy and increase ...
Source: JAMA Psychiatry - Category: Psychiatry Source Type: research
This study aims to investigate if sleep disturbances are related to cognitive impairments in schizophrenia spectrum (SCZ) and bipolar disorders (BD), if this relationship varies between different sleep disturbances (insomnia, hypersomnia or delayed sleep phase (DSP)) and lastly, if this relationship differs between clinical groups and healthy controls (HC). We included 797 patients (SCZ = 457, BD = 340) from the Norwegian Centre for Mental Disorders Research (NORMENT) study in Norway. Sleep disturbances were based on items from the Inventory of Depressive Symptoms-Clinician rated scale (IDS-C). ...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
Living with bipolar disorder can feel overwhelming. Maybe you’re tired of the ups and downs of different episodes—the soaring energy, the debilitating fatigue, the racing I-need-to-do-everything-and-I-need-to-do-it-now thoughts, and the dark, decelerated, bleak thoughts. Maybe you’re exhausted from struggling with an especially stubborn and deep depression, which makes it tough to concentrate on anything, and feels like you’re walking through a river of waist-high molasses in a fog. Managing bipolar disorder can feel overwhelming, too. What can make it much easier is getting effective treatment...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Disorders General Inspiration & Hope Mental Health and Wellness Self-Help Bipolar Disorder Depressive Episode Hypomania Manic Episode Mood Disorder Self Care self-compassion Source Type: blogs
Conclusions: Both interepisode bipolar and unipolar disorder patients had increased impulsivity compared to healthy individuals. There was no significant difference on attention and nonplanning impulsivity subscales; however, on the motor subscale, bipolar patients were more impulsive than unipolar disorder patients. PMID: 30992610 [PubMed]
Source: Indian Journal of Psychiatry - Category: Psychiatry Tags: Indian J Psychiatry Source Type: research
Conclusions: Sleep patterns in children and adolescents were related to the psychiatric diagnosis of their parent(s). Future follow-up of these results may clarify the relations between early sleep differences and the risk of developing mood disorders in individuals at high familial risk.IntroductionSleep disturbances are core symptoms of mood disorders including major depressive disorder and bipolar disorder (1). Additionally, sleep problems have been associated with more severe symptoms, greater functional impairment, and increased risk for relapse among individuals with mood disorders (2). Over 40% of children and youth...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
CONCLUSIONS: Sleep alterations frequently appear long before the onset of BD, and appear to be related specifically to the polarity of the index episode. The detection and treatment of sleep alterations in special high risk populations may help achieving an earlier detection of the illness. PMID: 30818134 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
ConclusionsSleep alterations frequently appear long before the onset of BD, and appear to be related specifically to the polarity of the index episode. The detection and treatment of sleep alterations in special high risk populations may help achieving an earlier detection of the illness.
Source: European Psychiatry - Category: Psychiatry Source Type: research
Authors: Verdolini N, Menculini G, Perugi G, Murru A, Samalin L, Angst J, Azorin JM, Bowden CL, Mosolov S, Young AH, Barbuti M, Popovic D, Vieta E, Pacchiarotti I, BRIDGE-II-MIX Study Group Abstract OBJECTIVE: This post hoc analysis of the BRIDGE-II-MIX study is aimed at evaluating affective lability (AL) as a possible clinical feature of mixed depression and assessing the relationship with atypical depressive features, particularly mood reactivity (MR). METHODS: In the BRIDGE-II-MIX multicenter, cross-sectional study, 2,811 individuals suffering from a major depressive episode (MDE; DSM-IV-TR criteria), in the...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
CONCLUSION: Milnacipran is a dual reuptake inhibitor of noradrenaline and serotonin, with greater effect on noradrenaline than serotonin, in contrast to the related drugs venlafaxine, desvenlafaxine and duloxetine. Rapidly absorbed irrespective of food, milnacipran has a half-life of approximately 8 hours, reaches steady state in 2 days and is excreted renally. Milnacipran helps a minority of patients with fibromyalgia by reducing pain and fatigue. It is also an effective antidepressant with efficacy comparable to venlafaxine and duloxetine, and a side effect profile characteristic of SNRIs. The dose range is...
Source: Australasian Psychiatry - Category: Psychiatry Authors: Tags: Australas Psychiatry Source Type: research
Authors: Wirz-Justice A, Ajdacic V, Rössler W, Steinhausen HC, Angst J Abstract The prevalence of autumn/winter seasonality in depression has been documented in the longitudinal Zurich cohort study by five comprehensive diagnostic interviews at intervals over more than 20 years (N = 499). Repeated winter major depressive episodes (MDE-unipolar + bipolar) showed a prevalence of 3.44% (5× more women than men), whereas MDE with a single winter episode was much higher (9.96%). A total of 7.52% suffered from autumn/winter seasonality in major and minor depressive mood states. ...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
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