The associations between self-reported depression, self-reported chronic inflammatory conditions and cognitive abilities in UK Biobank.
This study examined associations between self-reported depression and chronic inflammatory diseases and their interaction with cognitive performance in 456,748 participants of the UK Biobank, adjusting for sociodemographic and lifestyle factors. Numbers with available data ranged from 94,899 to 453,208 depending on the cognitive test. RESULTS: Self-reported depression was associated with poorer performance compared to controls in several cognitive tests (fully adjusted models, reaction time: B = 6.08, 95% CI = 5.09, 7.07; pairs matching: incidence rate ratio = 1.02, 95% CI =&thins...
Source: Journal of the Association of European Psychiatrists - June 5, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

How to design psychiatric facilities to foster positive social interaction - A systematic review.
Authors: Jovanović N, Campbell J, Priebe S Abstract Psychiatric facilities are often criticised of being poorly designed which may contribute to violent incidents and patients' complaints of feeling bored and lacking meaningful interactions with peers and staff. There is a lack of understanding how to design environments for staff, patients and visitors to engage in positive social interactions (e.g. conversation, sharing, peer support). We conducted a systematic literature review on which architectural typologies and design solutions facilitate helpful social interactions between users of psychiatric facilities. ...
Source: Journal of the Association of European Psychiatrists - May 23, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

People with severe problematic personality traits and offending histories: What influences occupational participation?
CONCLUSIONS: An intervention to increase prosocial occupational participation should be developed and evaluated for PDOs in the community, taking account of occupational participation over the life course. PMID: 31100608 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 19, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Associations of major depressive disorder with chronic physical conditions, obesity and medication use: Results from the PISMA-ep study.
Authors: Rivera M, Porras-Segovia A, Rovira P, Molina E, Gutiérrez B, Cervilla J Abstract BACKGROUND: Life expectancy of people with depression is on average 15 years less than that of the general population. This excess of mortality is largely attributed to a deteriorated physical health. Evidence about the association between major depressive disorder (MDD) and physical health is still lacking in some areas. The aim of this study was to explore the association between MDD and physical health-related variables in southern Spain. METHODS: The PISMA-ep is a cross-sectional study based on community-dwellin...
Source: Journal of the Association of European Psychiatrists - May 19, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Developmental trajectories of gambling severity after cognitive-behavioral therapy.
CONCLUSIONS: Our findings show that patients seeking treatment for GD are heterogeneous and that trends in progress following treatment can be identified considering sociodemographic features, psychopathological state and personality traits. These results could be useful in developing more efficient interventions for GD patients. PMID: 31100610 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 19, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The effects of transcranial direct current stimulation compared to standard bupropion for the treatment of tobacco dependence: A randomized sham-controlled trial.
CONCLUSIONS: The 12-week tDCS had a clinically good therapeutic effect on smoking cessation and its dependency. It may be a substitute for bupropion treatment. PMID: 31100611 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 19, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Association study of polymorphisms within inflammatory genes and methylation status in treatment response in major depression.
Authors: Draganov M, Arranz MJ, Salazar J, de Diego-Adeliño J, Gallego-Fabrega C, Jubero M, Carceller-Sindreu M, Portella MJ Abstract BACKGROUND: Although pharmacogenetics for major depressive disorder (MDD) is gaining momentum, the role of genetics in differences in response to antidepressant treatment is controversial, as they depend on multifactorial and polygenic phenotypes. Previous studies focused on the genes of the serotonergic system, leaving apart other pathological factors such as the inflammatory pathway. The main objective of the study was to assess whether treatment response might be associated...
Source: Journal of the Association of European Psychiatrists - May 19, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Prevalence of mental disorders and associated disability: Results from the cross-sectional CZEch mental health Study (CZEMS).
CONCLUSIONS: People with mental disorders have considerably elevated disability in comparison to mentally healthy participants. The prevalence of mental disorders in the Czech Republic is mostly in line with European prevalence rates but it is lower for anxiety disorders and two times higher for alcohol use disorders. PMID: 31096115 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 18, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

A century of sensory processing dysfunction in schizophrenia.
Authors: Dondé C, Avissar M, Weber MM, Javitt DC PMID: 31082567 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 16, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Clinical and socio-demographic characteristics associated with involuntary admissions in Switzerland between 2008 and 2016: An observational cohort study before and after implementation of the new legislation.
CONCLUSIONS: Besides schizophrenic or bipolar disorders, a small group of patients had an increased risk for IA due to non-clinical parameters (i.e. tourists and asylum seekers). Knowledge about risk factors should be used for the development of multi-level strategies to prevent frequent (involuntary) hospitalizations in patients at risk. On the organizational level, we could show that the new legislation decreased the risk for IA, and therefore may have succeeded in strengthening patient autonomy. PMID: 31079010 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 13, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Gender differences of patients at-risk for psychosis regarding symptomatology, drug use, comorbidity and functioning - Results from the EU-GEI study.
CONCLUSIONS: Findings indicate that gender differences in symptomatology and comorbidity in ARMS are similar to those seen in overt psychosis and in healthy controls. However, observed differences are small and would only be reliably detected in studies with high statistical power. Moreover, such small effects would likely not be clinically meaningful. PMID: 31075522 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 12, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Longitudinal studies of functional magnetic resonance imaging in first-episode psychosis: A systematic review.
CONCLUSIONS: This review of longitudinal FEP samples studies reveals a pattern of predominantly hypoactivation in several brain areas at baseline that may normalize to a certain extent after treatment. The results should be interpreted with caution given the small number of studies and their methodological and clinical heterogeneity. PMID: 31075523 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - May 12, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Predicting the incidence of non-suicidal self-injury in college students.
DISCUSSION: The college period carries high risk for the onset of NSSI. Individualized web-based screening may be a promising approach for detecting young adults at high risk for self-injury and offering timely intervention. PMID: 31035219 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - April 30, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The treatment gap for mental disorders and associated factors in the Czech Republic.
Authors: Kagstrom A, Alexova A, Tuskova E, Csajbók Z, Schomerus G, Formanek T, Mladá K, Winkler P, Cermakova P Abstract OBJECTIVES: To assess the extent of the treatment gap for mental disorders in the Czech Republic, determine factors associated with the utilization of mental health services and explore what influences willingness to seek mental health care. METHODS: Data from the CZEch Mental health Study, a nationally representative study of community-dwelling adults in the Czech Republic were used. The Mini International Neuropsychiatric Interview assessed the presence of mental disorders. 659...
Source: Journal of the Association of European Psychiatrists - April 23, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Effects of stimulant drug use on the dopaminergic system: A systematic review and meta-analysis of in vivo neuroimaging studies.
CONCLUSION: This meta-analysis provides evidence that there are ongoing changes in the dopaminergic system associated with the use of stimulants. Especially the results of cocaine, methamphetamine and amphetamine use mainly showed a downregulation. In addition, this meta-analysis is the first to include nicotine. This subset of studies showed evidence for a decreased receptor and DAT availability but no significant results were found in the metaanalyses. PMID: 30981746 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - April 16, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Emotion dysregulation and non-suicidal self-injury: A systematic review and meta-analysis.
CONCLUSIONS: Findings support the notion that greater emotion dysregulation is associated with higher risk for NSSI among individuals across settings, regardless of age or sex. Furthermore, findings reveal facets of dysregulation that may have unique implications for NSSI. This meta-analysis highlights the importance of better understanding emotion dysregulation as a treatment target for preventing NSSI. PMID: 30986729 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - April 16, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Association between prior somatic disease and 5-year relapse risk among 11,856 incident patients with schizophrenia.
Authors: Köhler-Forsberg O, Sørensen HJ, Benros ME, Petersen L, Gasse C Abstract BACKGROUND: Somatic diseases have been associated with an increased risk for subsequent schizophrenia; however, it is unknown whether prior somatic diseases negatively affect early treatment outcomes after a first-time schizophrenia diagnosis. METHODS: We included all individuals born in Denmark after January 1st, 1977 and first-time diagnosed with schizophrenia between January 1st, 1996 and December 31st, 2015. We identified all life-time somatic hospital contacts and all prescriptions within the year before the first-...
Source: Journal of the Association of European Psychiatrists - April 15, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Why and how to support depsychiatrisation of adult transidentity in ICD-11: A French study.
CONCLUSION: Results support depsychiatrisation. They are discussed in terms of medical, ethical, legal, and social, added values and implications of depsychiatrisation. PMID: 30981041 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - April 15, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Electroconvulsive therapy against the natural will: Some concerns.
Authors: Lenzen LM, Grözinger M Abstract In recent years, the scientific interest in "Electroconvulsive therapy (ECT) against the patient's natural" will has grown. Several publications have reported mostly positive outcomes in cases, where ECT has been implemented against the patient's natural will. The author's findings primarily indicate the effectiveness of ECT in non-consenting patients, which confirms earlier findings. All author's overall presumption turned out to be mainly positive. Within the discussion on involuntary ECT treatment, we missed disadvantageous arguments, which also need to be ...
Source: Journal of the Association of European Psychiatrists - March 19, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Differences in cognitive performance and cognitive decline across European regions: a population-based prospective cohort study.
DISCUSSION: There are substantial differences in cognitive performance as well as rates of cognitive decline among the elderly throughout European regions. This might be explained by differing levels of cognitive reserve. PMID: 30875582 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - March 17, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Short clinically-based prediction model to forecast transition to psychosis in individuals at clinical high risk state.
Authors: Kotlicka-Antczak M, Karbownik MS, Stawiski K, Pawełczyk A, Żurner N, Pawełczyk T, Strzelecki D, Fusar-Poli P Abstract OBJECTIVE: The predictive accuracy of the Clinical High Risk criteria for Psychosis (CHR-P) regarding the future development of the disorder remains suboptimal. It is therefore necessary to incorporate refined risk estimation tools which can be applied at the individual subject level. The aim of the study was to develop an easy-to use, short refined risk estimation tool to predict the development of psychosis in a new CHR-P cohort recruited in European country with less established early...
Source: Journal of the Association of European Psychiatrists - March 16, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Not recognized enough: The effects and associations of trauma and intellectual disability in severely mentally ill outpatients.
CONCLUSIONS: Significantly more SMI outpatients who screened positive for MID/BIF reported having experienced traumatic events than those who screened negative. Rates of all trauma categories were significantly higher in the screen-positive group, who were also more likely to have PTSD. Sexual abuse occurred more in all females but the SCIL positive women are even more often victim. Clinical practice has to pay more attention to all of these issues, especially when they occur together in a single patient. PMID: 30836316 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - March 7, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The optical-coenaesthetic disproportion in feeding and eating disorders.
Authors: Stanghellini G PMID: 30836317 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - March 7, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

A systematic review on sleep alterations anticipating the onset of bipolar disorder.
CONCLUSIONS: Sleep alterations frequently appear long before the onset of BD, and appear to be related specifically to the polarity of the index episode. The detection and treatment of sleep alterations in special high risk populations may help achieving an earlier detection of the illness. PMID: 30818134 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - March 4, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Rehabilitative compensatory mechanism of hierarchical subnetworks in major depressive disorder: A longitudinal study across multi-sites.
CONCLUSION: Although pathological lesion on MDD relied on abnormal core organization, disease remission was association with the compensation from non-core organization. These results suggested that the dysfunctions arising from hierarchical subnetworks are compensated by increased information interactions between core brain regions and functionally diverse regions. PMID: 30822739 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - March 4, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

High BDNF serum levels are associated to good cognitive functioning in bipolar disorder.
This study aimed to investigate the role of these neurobiological factors in clinical and cognitive outcomes in a sample of bipolar individuals. METHODS: We measured serum BDNF, cytokines and oxidative stress markers in a sample of 133 individuals: 52 euthymic bipolar patients, 32 manic patients and 49 healthy controls. They were all assessed with a comprehensive cognitive battery. Sociodemographic and clinical data were collected. Multiple linear regression models were built to study associations of neurotrophins and inflammatory and oxidative measures with cognitive functioning. RESULTS: BDNF levels were decrease...
Source: Journal of the Association of European Psychiatrists - February 28, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Direct medical costs of ADHD and its comorbid conditions on basis of a claims data analysis.
Authors: Libutzki B, Ludwig S, May M, Jacobsen RH, Reif A, Hartman CA Abstract BACKGROUND: ADHD is a highly prevalent disease in childhood which often persists into adulthood, then co-occurring with common adult conditions. Especially for adult ADHD, little is known about the costs of ADHD and the additional costs of comorbid conditions. AIMS: To determine medical costs of ADHD and costs of comorbidities (mood, anxiety and substance use disorders, obesity), including their co-occurrence rates, stratified by age and gender. METHOD: Claims data from a German Statutory Health Insurance database with approximat...
Source: Journal of the Association of European Psychiatrists - February 27, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Illness representations among parents of children and adults with serious mental disorders: A systematic review and theoretical model.
CONCLUSION: Parents struggle to make meaning of their child's illness, often holding stigmatizing ideas about the illness and blaming themselves for its existence. More longitudinal studies that include both of the child's parents, as well as interventional studies, are needed to expand our knowledge of ways to help parents construct more beneficial representations of their children's illnesses. PMID: 30769239 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - February 17, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Duration of untreated illness and response to SRI treatment in Obsessive-Compulsive Disorder.
CONCLUSIONS: Our results, although preliminary, seem to suggest that a longer duration of untreated illness in OCD is associated with poorer outcome in terms of response to SRI treatments. It is imperative to do all the possible to shorten the DUI, both by improving access to mental health services, improving the ability of primary care physicians and mental health professionals to recognize OCD, and disseminate best-practice prescription guidelines. PMID: 30763828 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - February 16, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Child maltreatment is mediating long-term consequences of household dysfunction in a population representative sample.
CONCLUSIONS: ACEs linked to household dysfunction are associated with an increased risk for all subtypes of child maltreatment. The assessed widespread consequences of household dysfunction are mediated by child maltreatment. This underlines the role of prevention of child maltreatment in families with household dysfunction and implies child protection as a priority in any interventions. PMID: 30743239 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - February 13, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors.
Authors: Fleischhacker W, Galderisi S, Laszlovszky I, Szatmári B, Barabássy Á, Acsai K, Szalai E, Harsányi J, Earley W, Patel M, Németh G Abstract BACKGROUND: Negative symptoms in schizophrenia are heterogeneous and multidimensional; effective treatments are lacking. Cariprazine, a dopamine D3-preferring D3/D2 receptor partial agonist and serotonin 5-HT1A receptor partial agonist, was significantly more effective than risperidone in treating negative symptoms in a prospectively designed trial in patients with schizophrenia and persistent, predominant negative symptoms. METHODS...
Source: Journal of the Association of European Psychiatrists - February 11, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Hippocampal subfield volumes in major depressive disorder and bipolar disorder.
CONCLUSION: We observed hippocampal subfield volume reductions in both MDD and BD, a finding which more prominent in MDD. The inverse correlation between BD illness duration and hippocampal subfield volume may evidence the neuroprogressive nature of BD. PMID: 30721801 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - February 7, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
CONCLUSION: Olanzapine, haloperidol plus promethazine or droperidol are most effective and safe for use as rapid tranquilisation. Midazolam sedates most quickly. But due to increased saturation problems, midazolam is restricted to use within an emergency department of a general hospital. PMID: 30721802 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - February 7, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

IL-10 is associated with increased mu-opioid receptor levels in major depressive disorder.
CONCLUSION: The results show that MOR levels may function as a possible component of the CIRS whilst there is no evidence that β-EP and EM-2 may modify the IRS. The significant correlation between MOR levels and IL-10 may be explained through central activation of the HPA-axis and increased B-cell numbers expressing MOR as a response to cytokine over-secretion in MDD. PMID: 30677547 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 25, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Characterization of Mood Instability through Bipolar Disorders: A cluster-analytic approach using weekly prospective life-chart methodology.
ConclusionBD type II presented higher MI and subsyndromal symptoms than BD type I patients. However, these differences did not translate into clinically relevant outcomes. A classification based on MI may provide useful clinical insights. PMID: 30677548 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 25, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The Research Domain Criteria (RDoC) and the historical roots of psychopathology: A viewpoint.
Authors: Stoyanov D, Correia DT, Cuthbert BN Abstract In this article we aim at conceptual reconstruction of the historical background behind RDoC project. It incorporates some elements that have not heretofore been included in frameworks for psychopathology research. At the same time, however, RDoC - like any approach to mental illness - must grapple with longstanding challenges in addressing issues about the roles and relationships of mind, brain, and patients' reports in considering the nature of disorder. In this respect, the historical roots of psychopathology remain as relevant as ever. PMID: 30677549 [Pu...
Source: Journal of the Association of European Psychiatrists - January 25, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Developmental cascades of internalising symptoms, externalising problems and cognitive ability from early childhood to middle adolescence.
CONCLUSIONS: In either childhood or adolescence, reducing behavioural problems could have both emotional and cognitive benefits. In childhood, improving cognitive skills could reduce both emotional and behavioural problems. PMID: 30677550 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 25, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Awareness and perceptions of clinical guidelines for the diagnostics and treatment of severe behavioural problems in children across Europe: A qualitative survey with academic experts.
CONCLUSIONS: This study offers a preliminary insight into the current successes and challenges perceived by experts around Europe associated with guidelines and documents for SBPs, acting as a stepping stone for future systematic, in-depth investigations of guidelines. Additionally, it establishes experts' consensus for the need to develop official guidelines better tailored to clinical practice, creating a momentum for a transition towards European clinical guidelines for this population. PMID: 30658274 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 20, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Cost-effectiveness analysis of collaborative treatment of late-life depression in primary care (GermanIMPACT).
CONCLUSION: Evidence for cost-effectiveness of GermanIMPACT relative to treatment as usual is not clear. Only if societal WTP was ≥€180 for an additional DFD, GermanIMPACT could be considered cost-effective with certainty. PMID: 30658275 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 20, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Prevalence of late-life depression and gap in mental health service use across European regions.
Conclusions We suggest that interventions to decrease the burden of late-life depression should be targeted at individuals that are affected by chronic somatic comorbidities and are limited in mental and physical functioning. Promotion of help-seeking of older adults, de-stigmatization of mental illness and education of general practitioners could help decrease the gap in mental health service utilization. PMID: 30658276 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 20, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Unmet needs in patients with brief psychotic disorders: Too ill for clinical high risk services and not ill enough for first episode services.
CONCLUSIONS: The majority of ATPDs are not detected/treated by EIS or CHR-P services, receive heterogeneous treatments and short-term clinical follow-up. ATPDs have a high risk of developing severe clinical outcomes beyond persistent psychotic disorders and unmet clinical needs that are not targeted by current mental health services. PMID: 30658277 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 20, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Effectiveness of CBT for children and adolescents with depression: A systematic review and meta-regression analysis.
CONCLUSIONS: There is evidence that CBT is effective for youth with a (subclinical) depression. Our analyses show that effects might improve when CBT contains the components behavioral activation and challenging thoughts and also when the caregiver(s) are involved. However, the influential effects of these three moderators should be further tested in RCTs. PMID: 30658278 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 20, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Attention-deficit/hyperactivity disorder symptoms and perceived mental health discrimination in adults in the general population.
CONCLUSION: ADHD symptoms are associated with higher odds for experiencing mental health discrimination and this association is especially elevated in those with the most severe ADHD symptoms. Interventions to inform the general public about ADHD may be important for reducing the stigma and discrimination associated with this disorder in adults. PMID: 30654318 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 18, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The utility of outpatient commitment: Reduced-risks of victimization and crime perpetration.
CONCLUSIONS: CTO assignment's association with reduced criminal-victimization and perpetration-risk, in conjunction with requiring participation in needed-treatment via re-hospitalization and community-service, adds support to the conclusion that OCC is to some extent fulfilling its legal objectives related to protecting safety of self (exclusive of deliberate-self-harm), and others. PMID: 30654319 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 18, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Long-term clinical and functional course of borderline personality disorder: A meta-analysis of prospective studies.
CONCLUSIONS: Findings suggest that the course of BPD is characterised by symptomatic amelioration and a slight functional improvement in the long-term. Age and gender modulate the long-term prognosis and should be considered to adapt treatment resources. Further research is required to draw robust conclusions on the long-term effects of psychotherapeutic interventions. PMID: 30599336 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - January 2, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

The mediating role of borderline personality features in the relationship between childhood trauma and psychotic-like experiences in a sample of help-seeking non-psychotic adolescents and young adults.
Authors: Sengutta M, Gawęda Ł, Moritz S, Karow A Abstract OBJECTIVE: Psychotic-like experiences (PLEs) often occur across different non-psychotic disorders in adolescent and young adult population and are related to early trauma. However, the mechanisms of how exposure to early trauma shapes the risk of PLEs are unclear. In our study, we investigated whether borderline personality features and further non-psychotic symptoms, i.e. factors related to both PLEs and childhood trauma, may mediate the relationship between childhood trauma and PLEs. METHODS: Two hundred inpatients aged 16-21 years who were treated d...
Source: Journal of the Association of European Psychiatrists - January 2, 2019 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Predictors of personal continuity of care of patients with severe mental illness: A comparison across five European countries.
CONCLUSION: Even in countries where exposure is decided through patient-clinician agreement, it was the admission hospital, not patient characteristics, that predicted exposure to care approaches. Nevertheless, organisational decisions in hospitals tend to expose socially disadvantaged patients to personal continuity. PMID: 30583254 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - December 26, 2018 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Predicting suicidal ideation by interpersonal variables, hopelessness and depression in real-time. An ecological momentary assessment study in psychiatric inpatients with depression.
CONCLUSIONS: This study provides further evidence on the short-term variability of SI in very short time frames implying the need of assessing SI repeatedly in clinical and research settings. The associations between interpersonal variables and passive and active SI were only partial in line with assumptions of the Interpersonal Theory of Suicide. Overall, the effects were small warranting further investigation. PMID: 30530103 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - December 12, 2018 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

Response to commentary by Grifell and Hart, commentary on: The problem of mephedrone in Europe: Causes and suggested solutions.
Authors: Ordak M, Nasierowski T PMID: 30500559 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - December 5, 2018 Category: Psychiatry Tags: Eur Psychiatry Source Type: research

A systematic review on the relationship between mental health, radicalization and mass violence.
In conclusion, this systematic review indicates that caution should be taken on how the association between 'mental health' and 'radicalization' is being claimed, because of limited evidence so far, and a number of methodological limitations of studies addressing this issue. PMID: 30500571 [PubMed - as supplied by publisher] (Source: Journal of the Association of European Psychiatrists)
Source: Journal of the Association of European Psychiatrists - December 5, 2018 Category: Psychiatry Tags: Eur Psychiatry Source Type: research