Plasma BNP Levels and Diuretics Use as Predictors of Cardiovascular Events in Patients with Myocardial Infarction and Impaired Glucose Tolerance

ConclusionsIn patients with MI and IGT, high plasma BNP levels predicted the occurrence of coronary stenosis, recurrent MI, and worsening of HF, whereas diuretic use did not predict the progression of coronary stenosis but non-fatal MI and worsening of HF.
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research

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Although heart failure is a common complication of myocardial infarction, prognostic tools and new therapies can help manage the condition. Here are some key facts.American College of Cardiology &Medscape
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Article Source Type: news
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson &Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelera...
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Source: Frontiers in Neurology - Category: Neurology Source Type: research
(Natural News) Heart attack survivors might feel apprehensive about exercising regularly. But a recent study showed that it can help prevent heart failure and increase their life expectancy over time. Published in the Journal of the American Heart Association (JAHA), the study revealed that survivors who remain physically active after a heart attack have a reduced risk...
Source: - Category: Consumer Health News Source Type: news
The treatment of hypertension in older adults is a major public health concern. Among the nearly 13 million persons in the United States aged 80 years or older, approximately 80% have high blood pressure (BP). Hypertension is the most potent modifiable risk factor for cardiovascular disease in older adults and has been strongly associated with stroke, myocardial infarction, heart failure, peripheral artery disease, kidney failure, and dementia. Thus, defining optimal strategies for managing elevated BP in older individuals is a high priority.
Source: JAMA - Category: General Medicine Source Type: research
ConclusionFXa inhibition with apixaban does not influence pathological cardiac remodelling after MI. These data do not support the use of FXa inhibitor in HF patients with the aim to amend the severity of HF.Graphical Abstract
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research
AbstractAn increase in left ventricular volumes between baseline and follow-up imaging is the main criteria for the quantification of left ventricular remodelling (LVR) after ST-elevation myocardial infarction (STEMI), but without consensual definition. We aimed to review the criteria used for the definition of LVR based on cardiac magnetic resonance imaging (CMR) in STEMI patients. A systematic literature search was conducted using MEDLINE and the Cochrane Library from January 2010 to August 2019. Thirty-seven studies involving 4209 patients were included. Among these studies, 30 (81%) used a cut-off value for defining LV...
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
Myocardial ischaemia is usually accompanied by inflammatory response which plays a critical role in the myocardial healing and scar formation, while persistent inflammatory response contributes greatly to the myocardial remodeling and consequent heart failure. Metformin (Met), a widely used hypoglycemic drug, has increasingly been shown to exert remarkable cardioprotective effect on ischaemic myocardial injury such as acute myocardial infarction (AMI). However, the underlying mechanisms are still far from being fully understood.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Source Type: research
DiscussionDANBLOCK is a randomized clinical trial investigating the effect of long-term beta-blocker therapy after myocardial infarction in patients without heart failure and reduced LVEF. Results from the trial will add important scientific evidence to inform future clinical guidelines.Trial,NCT03778554. Registered on 19 December 2018.European Clinical Trials Database,2018-002699-42, registered on 28 September 2018.
Source: Trials - Category: Research Source Type: clinical trials
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Heart Health Tests and procedures Source Type: blogs
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