Neuro-Clinical signatures of language impairments after acute stroke: a VBQ analysis of quantitative native CT scans.

CONCLUSION: In summary, the method applied to nCT scans performed in the acute stage of stroke provided robust and accurate information about brain lesions' location and size, as well as quantitative values. We found that nCT and VBQ analyses areeffective for identifying neural signatures of concomitant language impairments at the individual level, and neuroanatomical maps of aphasia at the population level. The signatures explicate the neurophysiological mechanisms underlying aetiology of the stroke. Ultimately, similar analyses with larger cohorts could lead to a more integrated multimodal model of behavior and brain anatomy in the early stage of ischemic stroke. PMID: 32066362 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32066362?dopt=Abstract

Source: Current Topics in Medicinal Chemistry - February 9, 2020 Category: Chemistry Authors: Muller S, Dauyey K, Ruef A, Lorio S, Eskandari A, Schneider L, Beaud V, Roggenhofer E, Draganski B, Michel P, Kherif F Tags: Curr Top Med Chem Source Type: research