Long-term Impact of Mini-Gastric Bypass on Inflammatory Cytokines in Cohort of Morbidly Obese Patients: a Prospective Study

AbstractPurposeOne anastomosis gastric bypass (OAGB) is a promising bariatric procedure. We performed this study to evaluate the changes in a group of inflammatory cytokines 12  months after OAGB.MethodsA single-arm prospective study was conducted on obese patients who underwent OAGB. The serum levels of the following adipocytokines were monitored pre- and 12  months postoperatively: adiponectin, leptin, interleukin 6 (IL-6), interleukin 8 (IL-8) levels, tumor necrosis factor-alpha (TNF-α), serum amyloid A (SAA), high-sensitivity C-reactive protein (hs-CRP), and monocyte chemotactic protein 1 (MCP-1).ResultsA total of 62 patients were included with a mean age of 43.9  ± 6.8 years old. The serum adiponectin increased significantly from 7.64 ± 0.29 to 8.76 ± 0.42 μg/mL 12 months after the operation (p 
Source: Obesity Surgery - Category: Surgery Source Type: research

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Bariatric surgery comprises a group of operative procedures designed to improve weight-related medical conditions. In the United States, these include vertical sleeve gastrectomy, Roux-en-Y gastric bypass, adjustable gastric banding, and the duodenal switch procedure. Bariatric surgery is the only durable and effective way for most humans to lose a significant amount of weight, and see improvement in obesity-related comorbidities. It can improve quality of life, prevent a number of cancers, and decrease overall mortality.
Source: Techniques in Vascular and Interventional Radiology - Category: Radiology Authors: Source Type: research
Bariatric surgery comprises a group of operative procedures designed to improve weight-related medical conditions. In the United States, these include vertical sleeve gastrectomy, Roux-en-Y gastric bypass, adjustable gastric banding, and the duodenal switch procedure. Bariatric surgery is the only durable and effective way for most humans to lose a significant amount of weight, and see improvement in obesity-related comorbidities. It can improve quality of life, prevent a number of cancers, and decrease overall mortality.
Source: Techniques in Vascular and Interventional Radiology - Category: Radiology Authors: Source Type: research
  That’s precisely what the American Academy of Pediatrics (AAP) is recommending: more weight loss surgery for overweight kids. This sort of perverted advice reflects the deep and widespread failure of the healthcare system to address nutrition and health, resorting instead to an awful surgical “solution” that, contrary to the AAP’s declaration that it is a proven safe option, is filled with complications, nutritional deficiencies, dysbiotic alterations in bowel flora, hormonal disruptions, and—not all that rarely—death. (Granted that it was over 10 years ago, but the first patient ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open bariatric surgery gastric bypass lap bad Weight Loss wheat belly Source Type: blogs
Publication date: Available online 2 August 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Jérémie Thereaux, Thomas Lesuffleur, Sébastien Czernichow, Arnaud Basdevant, Simon Msika, David Nocca, Bertrand Millat, Anne Fagot-CampagnaSummaryBackgroundConcerns are rising about the late adverse events following gastric bypass and sleeve gastrectomy. We aimed to assess, over a 7-year period, the late adverse events after gastric bypass and sleeve gastrectomy compared with matched control groups.MethodsIn this nationwide, observational, population-based, cohort study, we used data extracted from ...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Conclusions: Bariatric surgery appears to be capable of partially reversing the obesity-related epigenome. The identification of potential epigenetic biomarkers predictive for the success of bariatric surgery may open new doors to personalized therapy for severe obesity. Introduction Obesity is currently a huge healthcare problem, worldwide, and is a risk factor for several diseases such as type 2 diabetes (T2D), cardiovascular disease and cancer (1). As the prevalence of obesity reaches pandemic proportions, this metabolic disease is estimated to become the biggest cause of mortality in the near future (2). In fact,...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
ConclusionFrom the clinical case described and the analysis of the Literature, the advantages of this technique are clear, allowing for an easy endoscopic evaluation of gastric walls with the possibility of diagnosing early stage tumors with a better outcome for patients.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
AbstractBackgroundBariatric surgery is associated with a reduced risk of developing certain malignancies, particularly in women. However, the impact of bariatric surgery on tumor characteristics, cancer treatment, and oncologic outcomes is unknown.MethodIn a retrospective cohort study, 42 subjects diagnosed with breast cancer after bariatric surgery (1989 –2014) were matched to 84 subjects with breast cancer (1984–2012) who did not undergo bariatric surgery, based on age, body mass index (BMI), and menopausal status at the time of breast cancer diagnosis, as well as the date of cancer diagnosis. Medical records...
Source: Obesity Surgery - Category: Surgery Source Type: research
Bariatric surgery is the most effective therapy for patients with morbid obesity today [1]. However, the types of operation are still evolving. Sleeve gastrectomy (SG) recently has quickly gained popularity as a primary bariatric surgery worldwide [2,3]. SG plus duodeno-jejunostomy (SG-DJB) was introduced in 2007 as an alternative to Roux-en-Y gastric bypass (RYGB) because the issue of gastric cancer arising from the excluded stomach [4]. SG-DJB can be regarded as a modification of duodenal switch (DS) with short bypass limb and fewer nutritional problems [5].
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original article Source Type: research
Bariatric surgery is the most effective therapy for patients with morbid obesity today [1]. However, the types of operation are still in evolving. Sleeve gastrectomy (SG) recently has quickly gained popularity as a primary bariatric surgery worldwide [2, 3]. SG plus duodeno-jejunostomy (SG-DJB) was introduced in 2007 as an alternative to Roux-en-Y gastric bypass (RYGB) because the issue of gastric cancer arising from the excluded stomach [4]. SG-DJB can be regarded as a modification of duodenal switch (DS) with short bypass limb and fewer nutritional problems [5].
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
Background: In Brazil, the prevalence of obesity have increased 60% in the las 10 years. Obesity is related to metabolic diseases such as type 2 diabetes, hypertension, cardiovascular disease and cancer. The bariatric surgery is the best treatment for obesity when medical therapy fails. Roux-en-Y Gastric Bypass (RYGB) is one of the most commonly performed surgery to treat obesity, reducing 75% of the excess weight loss in the first year.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
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