Vitamin D and other environmental risk factors in Colombian patients with multiple sclerosis

Conclusion: We did not find a statistically significant association between MS and vitamin D levels while anti-EBV nuclear antigen titers behaved as previously described in the literature. This study provides new evidence of the association between MS and different risk factors in our country, reinforcing the hypothesis that the pathogenesis of MS is multifactorial. Further studies are needed to better define the association between environmental factors and the development of MS in low prevalence areas.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research

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AbstractMultiple sclerosis (MS) is an autoimmune disease, characterized by multiple demyelination of axons in both white and gray matter in the Central Nervous System (CNS). There is increasing evidence to support the notion that angiogenesis and chronic inflammation are mutually related. Different immune cells, including monocytes –macrophages, lymphocytes, neutrophils, mast cells (MCs) and dendritic cells are able to secrete an array of angiogenic cytokines, which promote growth, migration, and activation of endothelial cells. MCs play various roles in MS pathogenesis, influencing the innate immune response in peri...
Source: Inflammation Research - Category: Research Source Type: research
AbstractPurposeDespite the fact that the risk versus benefit of smoking cannabis has not been extensively studied, many individuals with multiple sclerosis are smoking cannabis to reduce their pain intensity and spasticity. The lack of information about inhaled cannabis might be attributed to the fact that most trials focus on orally administered cannabis. Given the fact that the administration of cannabis via inhalation is known to rapidly deliver cannabinoids with a higher total bioavailability than what can be achieved through oral or buccal routes, it is important to understand the clinical trials conducted using smoke...
Source: Inflammation Research - Category: Research Source Type: research
Conclusions: Our data confirm that the MS prevalence rate is high in Zanjan province of Iran.
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: November 2020Source: Multiple Sclerosis and Related Disorders, Volume 46Author(s): David Ellenberger, Peter Flachenecker, Judith Haas, Kerstin Hellwig, Friedemann Paul, Alexander Stahmann, Clemens Warnke, Uwe K. Zettl, Paulus S. Rommer, Scientific Advisory Group by the German MS-Register of the German MS Society
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Conclusions: This study introduced and evaluated a new method/protocol, SMMG, for studying muscle dynamics and demonstrated its feasibility for muscle contraction onset research. This novel technology can potentially provide new insights for future studies of neuromuscular diseases, such as multiple sclerosis and muscular dystrophy.
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
The company's product is a therapeutic equivalent generic version of Biogen's Tecfidera delayed-release capsules, the Hyderabad-based drug firm said in a statement.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Syndicated CBSN Boston CNN FDA Source Type: news
Side-effects of bexarotene rule out use but trial suggests other drugs may halt multiple sclerosisDoctors believe they are closer to a treatment for multiple sclerosis after discovering a drug that repairs the coatings around nerves that are damaged by the disease.A clinical trial of the cancer drug bexarotene showed that it repaired the protective myelin sheaths that MS destroys. The loss of myelin causes a range of neurological problems including balance, vision and muscle disorders, and ultimately, disability.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Multiple sclerosis Medical research Science Health Society Source Type: news
Publication date: December 2020Source: Journal of Transport &Health, Volume 19Author(s): Stephanie L. Silveira, Robert W. Motl
Source: Journal of Transport and Health - Category: Occupational Health Source Type: research
Conclusion: The results showed that the MLQ is a valid and reliable measure for assessing meaning in life that can be applied in research on meaning in life among other patient populations. PMID: 32963500 [PubMed - in process]
Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
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