Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats

ConclusionThe combinatorial treatment of SNX and captopril lowered blood pressure through adjusting NO/NOS, ET-1 and dyslipidemia profile. Furthermore, this treatment alleviated the kidney damage via reducing the release of inflammatory factors and the expression of apoptotic markers. Therefore, these results provided a rationale for future clinical use of SNX combined with captopril in antihypertensive and protecting renal functions in hypertension.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research