Rationale and design of the quantification of myocardial blood flow using dynamic PET/CTA-fused imagery (DEMYSTIFY) to determine physiological significance of specific coronary lesions

ConclusionsSuccess of these developments should lead to the following benefits: (1) eliminate unnecessary invasive coronary angiography in patients with no significant lesions, (2) avoid stenting physiologically insignificant lesions, (3) guide percutaneous coronary interventions process to the location of significant lesions, (4) provide a flow-color-coded 3D roadmap of the entire coronary tree to guide bypass surgery, and (5) use less radiation and lower the cost from unnecessary procedures.Trial registryThe DEMYSTIFY study has been registered on ClinicalTrials.gov with registration number NCT04221594.

Source: Journal of Nuclear Cardiology - February 4, 2020 Category: Nuclear Medicine Source Type: research