Respiratory viral infection in lung transplantation induces exosomes that trigger chronic rejection

In this study, we determined whether symptomatic respiratory viral infections after lung transplantation induce circulating exosomes that contain lung-associated self-antigens and assessed whether these exosomes activate immune responses to self-antigens.

Source: The Journal of Heart and Lung Transplantation - January 20, 2020 Category: Transplant Surgery Authors: Muthukumar Gunasekaran, Sandhya Bansal, Ranjithkumar Ravichandran, Monal Sharma, Sudhir Perincheri, Francisco Rodriguez, Ramsey Hachem, Cynthia E. Fisher, Ajit P. Limaye, Ashraf Omar, Michael A. Smith, Ross M. Bremner, Thalachallour Mohanakumar Tags: ORIGINAL PRE-CLINICAL SCIENCE Source Type: research