Grand Challenge on Chronic Pain - NIH

The ChallengeChronic pain is a major public health problem, and treatments are limited. More research is needed to fully understand how acute pain evolves into chronic pain, and who will transition from acute to chronic pain. The Blueprint Grand Challenge on Chronic Pain seeks to shed light on the molecular, cellular and circuit-level changes – or neuroplasticity – underlying chronic pain. A key element of the program is to form research collaborations between experts on pain and experts on neuroplasticity.Mechanisms of SupportThe Grand Challenge on Chronic Pain supports research through:Multi-PI R01 grants focused on understanding the maladaptive changes that occur during the transition from acute to chronic pain.Competitive revisions that propose a collaborative, one year pilot study or a new specific aim associated with an active NIH grant. These initial studies are expected to lead to long term collaborations focused on chronic pain.Mechanisms Regulating Vesicular Axonal Transport Following Nerve InjuryValeria CavalliWashington University St. LouisAltered Sensibility Following Peripheral Nerve DamageClifford WoolfChildren's Hospital BostonPreventing Transition of Acute-to-Chronic Neuropathic Pain: Models, Mechanisms & InterventionsLinda WatkinsUniversity of Colorado at BoulderVGF, Critical Role in the Transition from Acute to Chronic PainLyudmila VulchanovaUniversity of Minnesota Twin CitiesEpigenetic and Genetic Contributors to Chronic Ne...
Source: Psychology of Pain - Category: Psychiatrists and Psychologists Source Type: blogs