Advancing Mesenchymal Stem Cell Therapy with CRISPR/Cas9 for Clinical Trial Studies.

In this study, we review the recent studies that explore CRISPR potency in gene engineering of MSCs, which have great relevance in MSC-based therapies. However, CRISPR/Cas technology make possible specific targeting of loci in target genes, but next-generation MSC-based therapies to achieve extensive clinical application need dedicated efforts. PMID: 31974923 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31974923?dopt=Abstract

Source: Advances in Experimental Medicine and Biology - January 26, 2020 Category: Research Tags: Adv Exp Med Biol Source Type: research