Salinomycin suppresses tumorigenicity of liver cancer stem cells and Wnt/beta-catenin signaling.

CONCLUSION: Salinomycin could suppress stemness properties and induce differentiation of LCSCs through the Wnt/β-catenin signaling pathway, which provides evidence that salinomycin may serve as a potential drug for liver cancer therapy targeting LCSCs in the clinic.
PMID: 31971116 [PubMed - as supplied by publisher]

Source: Current Stem Cell Research and Therapy - January 22, 2020 Category: Stem Cells Authors: Liu Q, Sun J, Luo Q, Ju Y, Song G Tags: Curr Stem Cell Res Ther Source Type: research