Associations Between Obesity and the Effectiveness of Anti-Tumor Necrosis Factor- α Agents in Inflammatory Bowel Disease Patients: A Literature Review and Meta-analysis.

Conclusion and Relevance: In our meta-analysis, obesity was associated with the inferior response of anti-TNF treatments in UC patients. Clinicians should be aware that obese UC patients may require higher doses in anti-TNF treatment. PMID: 31955605 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31955605?dopt=Abstract

Source: The Annals of Pharmacotherapy - January 18, 2020 Category: Drugs & Pharmacology Authors: Dai ZH, Xu XT, Ran ZH Tags: Ann Pharmacother Source Type: research