Using Neuromodulation to Treat Premature Ejaculation

Men’s sexual health and wellness company, Morari Medical is using neuromodulation for its wearable device to help treat premature ejaculation (PE). The Maple Grove, MN-based company debuted a prototype of the patch-like device at the Consumer Electronics Show in Las Vegas earlier this month. Morari was one of 10 companies in the emerging sextech market to have a presence at the show. Jeff Bennett, the company’s founder and CEO spoke with MD+DI about the Morari Medical and its mission. “Specifically, we’re trying to address the medical condition of PE, which affects 30% of men,” Bennett told MD+DI. “With my prior experience with working at Medtronic and having experience with neuromodulation products, I knew that the use of electrical energy can use or affect many different clinical disorders including the brain for Parkinson’s; the bladder for overactive bladder; and the heart for arrhythmias. So, I thought why not take it from there.” The disposable device is placed on the perineum - “the area between the anus and the posterior part of the external genitalia.” Here’s how it works. “We’ve got a flexible circuit board that can be flexed to fit in the perineum area and on that board are electrodes that receive electrical energy from a battery that&...
Source: MDDI - Category: Medical Devices Authors: Tags: Electronics Source Type: news

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Parkinson ’s Disease is a condition characterized by degeneration of the nigrostriatal pathways resulting in marked bradykinesia. Studies have reported that nearly 25% of Medicare beneficiaries with Parkinson’s Disease reside in long-term care facilities (LTCFs). Residents of LTCFs are older and may also have other age-related mobility disorders. It is important for providers to know that Parkinsonism symptoms can also occur as a result of natural aging and will not respond to standard therapy for Parkinson’s Disease.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Source Type: research
Parkinson ’s disease (PD) is a multifaceted condition that impacts a wide range of functions, including speech. The effect of loss of communication ability creates a cascade of effects which includes decreased participation in social events, social isolation, and potentially depression. If improvements in v oice occur, the cascade can be diverted. A physiological basis, as well as research evidence, supports use of singing to improve voice of those with PD. The implementation of a choir for those with PD has the potential to provide a socially engaging intervention, which is cost effective.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Source Type: research
Authors: Morris G, Maes M, Berk M, Carvalho AF, Puri BK Abstract Nutritional ketosis, induced via either the classical ketogenic diet or the use of emulsified medium-chain triglycerides, is an established treatment for pharmaceutical resistant epilepsy in children and more recently in adults. In addition, the use of oral ketogenic compounds, fractionated coconut oil, very low carbohydrate intake, or ketone monoester supplementation has been reported to be potentially helpful in mild cognitive impairment, Parkinson's disease, schizophrenia, bipolar disorder, and autistic spectrum disorder. In these and other neurode...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Associations Between APOE Variants, Tau and α-Synuclein. Adv Exp Med Biol. 2019;1184:177-186 Authors: Rodriguez-Vieitez E, Nielsen HM Abstract Neurodegenerative diseases are characterized by the aggregation and deposition of misfolded proteins in the brain, most prominently amyloid-β (Aβ), tau and α-synuclein (α-syn), and are thus referred to as proteinopathies. While tau is a hallmark of Alzheimer's disease (AD) and other non-AD tauopathies, and α-synuclein is the pathological feature of the spectrum of synucleinopathies including Parkinson's disease (PD), Parkinson's...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
This study aimed to explore the time-effect of color duplex Doppler ultrasound (CDDU) in the diagnosis of vascular erectile dysfunction (ED). MATERIAL AND METHODS: Using a self-control study, we included patients who underwent penile CDDU and cavernosography in our hospital. We compared the arterial peak systolic velocity (PSV) of CDDU among different intervals for the diagnosis of arterial ED. We included 357 patients who were under consideration for vascular ED. RESULTS: We found significant differences in all the pairwise comparison of PSV in the 1st (0-5 min), 2nd (6-10 min), 3rd (11-15 min), and 4th (16-20 min...
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
WEDNESDAY, Feb. 26, 2020 -- A spirited game of ping pong may be more than just fun: New research suggests it could quell symptoms in Parkinson's patients. The small study found that patients with the movement disorder had significant improvements...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
This article explores relevant evidence on the involvement of astrocytes in experimental PD neurodegeneration from a molecular signaling perspective. For a long time, astrocytic proliferation was merely considered a byproduct of neuroinflammation, but by the time being, it is clear that astrocytic dysfunction plays a far more important role in PD pathophysiology. Indeed, ongoing experimental evidence suggests the importance of astrocytes and dopaminergic neurons' cross-linking signaling pathways. The Wnt-1 (wingless-type MMTV integration site family, member 1) pathway regulates several processes including neuron survival, ...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
Scientists from Fukuoka University in Japan found five hours' of playing time a week reduced tremors, limb rigidity, slowness of movement and balance for at least six months.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusions: RT, despite modern techniques, affects the sexual function of PCa patients in varying degrees. Reducing radiation doses to penile structures may play a role in preventing erectile dysfunction.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
AbstractBackgroundDeep brain stimulation (DBS) in the subthalamic nucleus (STN) is used in advanced Parkinson ’s disease (PD) for reducing motor fluctuations and the side effects of antiparkinsonian medication (APM). The development of neuroimaging has enabled the direct targeting of the STN. The aim of this study is to evaluate the outcome in patients with PD using STN DBS when changing from atlas-based indirect targeting method (iTM) to direct MRI-based targeting (dTM) assuming dTM is superior.MethodsTwenty-five consecutive PD patients underwent dTM STN DBS surgery from 2014 to 2017 with follow-up for 1  year....
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
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