Favorable prognostic impact of Natural Killer cells and T cells in high-grade serous ovarian carcinoma.

Conclusions: In patients with HGSC tumor-infiltrating CD57+ NK cells and CD8+ T cells had favorable prognostic impact, while PD-L1 expression had borderline favorable prognostic significance. CD66b + neutrophils had no prognostic association. These findings may influence future immunotherapy development. PMID: 31931651 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31931651?dopt=Abstract

Source: Acta Oncologica - January 13, 2020 Category: Cancer & Oncology Authors: Henriksen JR, Donskov F, Waldstrøm M, Jakobsen A, Hjortkjaer M, Petersen CB, Dahl Steffensen K Tags: Acta Oncol Source Type: research