Biological convergence of three human and animal model quantitative trait loci for blood pressure

Conclusions:
Two pathogenic pathways of hypertension biologically unify mechanisms of BP regulations for humans and their functional surrogates. The mechanism-based biology for the M3R-mediated pathway in raising BP has established M3R as a novel pathogenesis-driven target for antihypertension therapies.

Source: Journal of Hypertension - January 10, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Experimental hypertension Source Type: research