Nonopioid analgesics for perioperative and cardiac surgery pain in children: Current evidence and knowledge gaps

Conclusion: Nonopioid medications appear to show promise for analgesia in infants undergoing cardiac surgery, with ketorolac being the most potent agent as a potential substitute for opioids. These agents demonstrate a reasonable safety profile even in the very young. There continue to be significant gaps in knowledge before their adoption becomes routine. However, gives the awareness regarding short-term and long-term impact of opioid use in this vulnerable population, and studies of such agents are an urgent need.
Source: Annals of Pediatric Cardiology - Category: Cardiology Authors: Source Type: research