Fetal outcomes after intentional ingestion of paraquat: A case report

We report the case of a pregnant woman who took paraquat intentionally. Patient concerns: A 36-year-old woman at 38+ weeks gestational age, in an apparent suicide attempt, drank 1 mouthful (about 20 ml) of paraquat solution. Ten hours later, her urine dithionate test showed light blue color with a plasma paraquat concentration of 0.547 μg/ml. Six hours after admission, a male infant, whose plasma paraquat concentration was 0.761 μg/ml, together with 0.673 μg/ml in the amniotic fluid measured by high-performance liquid chromatography, was delivered but the woman's lung, liver, and kidney function declined rapidly. Diagnosis: 1.Acute paraquat poisoning;2.Third trimester of pregnancy (38+ weeks);3.Placenta previa. Interventions: Because of placenta previa and multiple organ failure, emergency cesarean section, and panhysterectomy were performed for the pregnant woman. Intravenous injection of antibiotic to prevent infection and dexamethasone 30 mg once a day were administered. Mechanical ventilation was performed for the infant and meropenem and penicillin injection was administered. Outcomes: The infant died 33 hours after birth while the mother died on the 3rd day after ingestion. Lessons: Paraquat can enter the fetus through the placenta and the amniotic fluid via fluid exchange. The pathological changes of fetal organs may relate to gestational age, and the prognosis was very poor in both the mother and the fetus.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

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Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcoholism alcohol abuse alcohol dependence alcohol dependency alcohol detox alcohol treatment alcohol treatment center alcohol treatment facility alcohol use risks Source Type: blogs
Discussion “[Cannabis] is a genus of flowering plant with three main varieties: sativa, indica and ruderalis.” It has been used for hundreds of years for hemp or fiber and also for psychoactive and medicinal effects. The active compounds are collectively called cannabinoids, of which delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most abundant. The floral buds or calyxes of the plant have the most cannabinoids, but other parts of the plant are also used such as leaves. Hash oil, hashish (or resin) and marijuana (dried leaves) are the common products from strongest to least strongest products. ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
CONCLUSIONS: Single product suicidal poisonings were more frequent with extremes of age and in pregnancy. OTC products were more frequently used in single product attempts. Products causing serious clinical effects can be targeted for suicide prevention efforts as well as education of health care providers. PMID: 30430638 [PubMed - as supplied by publisher]
Source: Suicide and Life-Threatening Behavior - Category: Psychiatry & Psychology Authors: Tags: Suicide Life Threat Behav Source Type: research
[Gender Links] Maseru -"I woke up this morning and a nurse told me that I have been I a comma since I came in," says Ntsoaki* from her bed in Lesotho's only referral hospital. "I don't know where I will go when I leave the hospital. I do not have money to pay and I do not have any clothes with me. I was not trying to abort the baby, I was trying to commit suicide using rat poison because my boyfriend did not want the baby and my mother said she could not support us. Unfortunately for me I survived and only my baby died."
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
CONCLUSIONS: Tox Info Suisse recorded an average of 137 cases of agent exposure during pregnancy per year, mostly due to accidents with household products. Suicidal intentions played a role in a considerable number of exposures. Measures are needed to prevent accidental exposure of pregnant women to toxic substances and to support them in this exceptional life period. PMID: 29767826 [PubMed - in process]
Source: Swiss Medical Weekly - Category: General Medicine Authors: Tags: Swiss Med Wkly Source Type: research
[Abstract unavailable] Language: en...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Authors: Ozturk Z, Ugras K PMID: 29537318 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
CONCLUSIONS: The study showed gender differentials in the determinants of self-harm mortality among youth in SA. For this reason, uniform approaches to awareness campaigns need to be altered to address the specific needs of youth. While males have higher rates than females, the prevalence of self-harm mortality in pregnant females is of concern and needs to be addressed specifically, as it relates not only to suicidal ideation and behaviour but also to youth sexual and reproductive health programmes in the country. PMID: 29262970 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
ConclusionsA low educational level is associated with the increased risk of premature death among women with a history of teenage pregnancy, except for suicide. Extra efforts should be made to encourage pregnant teenagers to continue education, and to provide psychosocial support to teenagers who undergo induced abortion.
Source: The European Journal of Public Health - Category: General Medicine Source Type: research
Conclusions: The studies conducted to date were limited in number with suggestive but methodologically weak findings related to chronic exposure. Given the wide-scale use of neonics, more studies are needed to fully understand their effects on human health. Citation: Cimino AM, Boyles AL, Thayer KA, Perry MJ. 2017. Effects of neonicotinoid pesticide exposure on human health: a systematic review. Environ Health Perspect 125:155–162; http://dx.doi.org/10.1289/EHP515 Address correspondence to M.J. Perry, Department of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington Un...
Source: EHP Research - Category: Environmental Health Authors: Tags: Reviews February 2017 Source Type: research
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