Cerebral Small Vessel Disease and Renal Function: Systematic Review and Meta-Analysis

Conclusion: We found no specific association between renal impairment and lacunar stroke, but we did find that in individuals who had not had a stroke, having more SVD features on imaging was associated with a worse renal function, which remained significant after controlling for hypertension. However, this finding does not exclude a powerful co-associate effect of age or vascular risk factor exposure. Future research should subtype lacunar stroke sensitively and control for major risk factors.Cerebrovasc Dis 2015;39:39-52
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research